CATH Domain 4hogA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q6FPH0_CANGA

[Candida] glabrata CBS 138

Uncharacterized protein

PDB Structure

PDB	4HOG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata. G-Dayanandan, N., Paulsen, J.L., Viswanathan, K., Keshipeddy, S., Lombardo, M.N., Zhou, W., Lamb, K.M., Sochia, A.E., Alverson, J.B., Priestley, N.D., Wright, D.L., Anderson, A.C. J.Med.Chem.