CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P49674
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P49674
KC1E_HUMAN
Homo sapiens
Casein kinase I isoform epsilon

PDB Structure

PDB 4HNI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the potent and selective inhibition of casein kinase 1 epsilon.
Long, A.M., Zhao, H., Huang, X.
J.Med.Chem.