CATH Domain 4hk2A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family	Polyubiquitin-C

Enzyme Information

UniProtKB Entries (1)

UBC_HUMAN

Homo sapiens

Polyubiquitin-C

PDB Structure

PDB	4HK2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization Zhang, Y., Zhou, L., Rouge, L., Phillips, A.H., Lam, C., Liu, P., Sandoval, W., Helgason, E., Murray, J.M., Wertz, I., Corn, J.E. to be published