CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.110 | Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase |
|
3.60.110.10 | Carbon-nitrogen hydrolase |
Domain Context
CATH Clusters
| Superfamily | Carbon-nitrogen hydrolase |
| Functional Family | Deaminated glutathione amidase |
Enzyme Information
| 3.5.1.128 |
Deaminated glutathione amidase.
based on mapping to UniProt P47016
N-(4-oxoglutaryl)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine.
-!- The enzyme, present in animals, fungi and bacteria, is involved in clearing cells of the toxic compound deaminated glutathione, which can be produced as an unwanted side product by several transaminases.
|
UniProtKB Entries (1)
| P47016 |
NIT2_YEAST
Saccharomyces cerevisiae S288C
Deaminated glutathione amidase
|
PDB Structure
| PDB | 4HG5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2
Acta Crystallogr.,Sect.D
|
