CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.1280 | Monooxygenase |
|
1.20.1280.70 | Exonuclease ExoI, domain 3 |
Domain Context
CATH Clusters
| Superfamily | Exonuclease ExoI, domain 3 |
| Functional Family | Exodeoxyribonuclease I |
Enzyme Information
| 3.1.11.1 |
Exodeoxyribonuclease I.
based on mapping to UniProt P04995
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for single-stranded DNA. -!- The Escherichia coli enzyme hydrolyzes glucosylated DNA. -!- Similar enzymes; mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases. -!- Formerly EC 3.1.4.25.
|
UniProtKB Entries (1)
| P04995 |
EX1_ECOLI
Escherichia coli K-12
Exodeoxyribonuclease I
|
PDB Structure
| PDB | 4HCB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structures of Escherichia coli exonuclease I in complex with the single strand DNA
To be published
|