CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | GTP-binding nuclear protein Ran |
Enzyme Information
UniProtKB Entries (2)
| P62826 |
RAN_HUMAN
Homo sapiens
GTP-binding nuclear protein Ran
|
| P30822 |
XPO1_YEAST
Saccharomyces cerevisiae S288C
Exportin-1
|
PDB Structure
| PDB | 4HB2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA
|