CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family |
Enzyme Information
UniProtKB Entries (2)
| P62826 |
RAN_HUMAN
Homo sapiens
GTP-binding nuclear protein Ran
|
| P30822 |
XPO1_YEAST
Saccharomyces cerevisiae S288C
Exportin-1
|
PDB Structure
| PDB | 4HB0 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.
Proc.Natl.Acad.Sci.USA
|
