CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1790 | Indigoidine synthase fold |
|
3.40.1790.10 | Indigoidine synthase domain |
Domain Context
CATH Clusters
| Superfamily | Indigoidine synthase domain |
| Functional Family | Indigoidine synthase A family protein |
Enzyme Information
| 4.2.1.70 |
Pseudouridylate synthase.
based on mapping to UniProt P33025
Uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H(2)O.
-!- The reaction it readily reversible. -!- While the enzymes from Tetrahymena pyriformis and Agrobacterium tumefaciens produce pseudouridine 5'-phosphate the enzyme from Escherichia coli functions as a pseudouridine-5'-phosphate glycosidase in vivo.
|
UniProtKB Entries (1)
| P33025 |
PSUG_ECOLI
Escherichia coli K-12
Pseudouridine-5'-phosphate glycosidase
|
PDB Structure
| PDB | 4GIJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Pseudouridine monophosphate glycosidase: a new glycosidase mechanism.
Biochemistry
|
