CATH Classification

Domain Context

CATH Clusters

Superfamily Hedgehog/Intein (Hint) domain
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P74750
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P74750
DPO3A_SYNY3
Synechocystis sp. PCC 6803 substr. Kazusa
DNA polymerase III subunit alpha

PDB Structure

PDB 4GIG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A conserved threonine spring-loads precursor for intein splicing.
Dearden, A.K., Callahan, B., Roey, P.V., Li, Z., Kumar, U., Belfort, M., Nayak, S.K.
Protein Sci.