CATH Domain 4gawA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Complement factor D

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt P20718

UniProtKB Entries (1)

GRAH_HUMAN

Homo sapiens

Granzyme H

PDB Structure

PDB	4GAW
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of SERPINB1 as a physiological inhibitor of human granzyme H Wang, L., Li, Q., Wu, L., Liu, S., Zhang, Y., Yang, X., Zhu, P., Zhang, H., Zhang, K., Lou, J., Liu, P., Tong, L., Sun, F., Fan, Z. J.Immunol.