CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.50 | 3-Layer(bba) Sandwich |
|
3.50.50 | FAD/NAD(P)-binding domain |
|
3.50.50.100 |
Domain Context
CATH Clusters
| Superfamily | 3.50.50.100 |
| Functional Family | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial |
Enzyme Information
| 1.6.5.9 |
NADH:ubiquinone reductase (non-electrogenic).
based on mapping to UniProt P32340
NADH + ubiquinone = NAD(+) + ubiquinol.
-!- Occurs in mitochondria of yeast and plants, and in aerobic bacteria. -!- Has low activity with NADPH.
|
UniProtKB Entries (1)
| P32340 |
NDI1_YEAST
Saccharomyces cerevisiae S288C
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial
|
PDB Structure
| PDB | 4G9K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates.
Proc.Natl.Acad.Sci.USA
|
