1 keywords

CATH Domain 4g74A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.50 3-Layer(bba) Sandwich
Topology 3.50.50 FAD/NAD(P)-binding domain
Homologous Superfamily 3.50.50.100  

Domain Context

CATH Clusters

Superfamily 3.50.50.100
Functional Family Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

Enzyme Information

1.6.5.9
NADH:ubiquinone reductase (non-electrogenic).
based on mapping to UniProt P32340
NADH + ubiquinone = NAD(+) + ubiquinol.
-!- Occurs in mitochondria of yeast and plants, and in aerobic bacteria. -!- Has low activity with NADPH.

UniProtKB Entries (1)

P32340
NDI1_YEAST
Saccharomyces cerevisiae S288C
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

PDB Structure

PDB 4G74
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insight into the type-II mitochondrial NADH dehydrogenases.
Feng, Y., Li, W., Li, J., Wang, J., Ge, J., Xu, D., Liu, Y., Wu, K., Zeng, Q., Wu, J.W., Tian, C., Zhou, B., Yang, M.
Nature