CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
Enzyme Information
UniProtKB Entries (2)
| Q8VDU0 |
GPSM2_MOUSE
Mus musculus
G-protein-signaling modulator 2
|
| P63096 |
GNAI1_HUMAN
Homo sapiens
Guanine nucleotide-binding protein G(i) subunit alpha-1
|
PDB Structure
| PDB | 4G5Q |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
|