CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.30 | Glutaredoxin |
|
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
| Superfamily | Glutaredoxin |
| Functional Family | Glutathione S-transferase, omega |
Enzyme Information
| 1.8.5.7 |
Glutathionyl-hydroquinone reductase.
based on mapping to UniProt P42620
Glutathione + 2-(glutathione-S-yl)-hydroquinone = glutathione disulfide + hydroquinone.
-!- This type of enzymes, which are found in bacteria, halobacteria, fungi, and plants, catalyze the glutathione-dependent reduction of glutathionyl-hydroquinones. -!- The enzyme from the bacterium Sphingobium chlorophenolicum can act on halogenated substrates such as 2,6-dichloro-3-(glutathione-S-yl)- hydroquinone and 2,3,5-trichloro-6-(glutathione-S-yl)-hydroquinone. -!- Substrates for these enzymes are often formed spontaneously by interaction of benzoquinones with glutathione.
|
UniProtKB Entries (1)
| P42620 |
YQJG_ECOLI
Escherichia coli K-12
Glutathionyl-hydroquinone reductase YqjG
|
PDB Structure
| PDB | 4G0K |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural understanding of the glutathione-dependent reduction mechanism of glutathionyl-hydroquinone reductases.
J.Biol.Chem.
|
