CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha-macroglobulin, receptor-binding domain
Functional Family Complement C4 isoform-A

Enzyme Information

UniProtKB Entries (1)

O00187
MASP2_HUMAN
Homo sapiens
Mannan-binding lectin serine protease 2

PDB Structure

PDB 4FXG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for activation of the complement system by component C4 cleavage.
Kidmose, R.T., Laursen, N.S., Dobo, J., Kjaer, T.R., Sirotkina, S., Yatime, L., Sottrup-Jensen, L., Thiel, S., Gal, P., Andersen, G.R.
Proc.Natl.Acad.Sci.USA
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