CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.220 | Intramolecular trans-sialidase; domain 3 | |
2.40.220.10 | Intramolecular Trans-sialidase; Domain 3 |
Domain Context
CATH Clusters
Superfamily | Intramolecular Trans-sialidase; Domain 3 |
Functional Family |
Enzyme Information
3.2.1.18 |
Exo-alpha-sialidase.
based on mapping to UniProt Q54727
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
-!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15.
|
UniProtKB Entries (1)
Q54727 |
NANB_STRPN
Streptococcus pneumoniae TIGR4
Sialidase B
|
PDB Structure
PDB | 4FOV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Synthesis and structural characterisation of selective non-carbohydrate-based inhibitors of bacterial sialidases.
Chembiochem
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