CATH Classification

Domain Context

CATH Clusters

Superfamily 2.70.98.70
Functional Family

Enzyme Information

4.2.2.8
Heparin-sulfate lyase.
based on mapping to UniProt Q89YR9
Elimination of sulfate, appears to act on linkages between N-acetyl-D- glucosamine and uronate. Product is an unsaturated sugar.
-!- Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages.

UniProtKB Entries (1)

Q89YR9
HEPC_BACTN
Bacteroides thetaiotaomicron VPI-5482
Heparin-sulfate lyase

PDB Structure

PDB 4FNV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of heparan sulfate-specific degradation by heparinase III.
Dong, W., Lu, W., McKeehan, W.L., Luo, Y., Ye, S.
Protein Cell
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