CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.50 | Alpha/alpha barrel |
|
1.50.10 | Glycosyltransferase |
|
1.50.10.100 | Chondroitin AC/alginate lyase |
Domain Context
CATH Clusters
| Superfamily | Chondroitin AC/alginate lyase |
| Functional Family |
Enzyme Information
| 4.2.2.8 |
Heparin-sulfate lyase.
based on mapping to UniProt Q89YR9
Elimination of sulfate, appears to act on linkages between N-acetyl-D- glucosamine and uronate. Product is an unsaturated sugar.
-!- Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages.
|
UniProtKB Entries (1)
| Q89YR9 |
HEPC_BACTN
Bacteroides thetaiotaomicron VPI-5482
Heparin-sulfate lyase
|
PDB Structure
| PDB | 4FNV |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis of heparan sulfate-specific degradation by heparinase III.
Protein Cell
|