CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Calcium/calmodulin-dependent protein kinase type 1

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q14012
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q14012
KCC1A_HUMAN
Homo sapiens
Calcium/calmodulin-dependent protein kinase type 1

PDB Structure

PDB 4FG9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of human CaMKIalpha reveal insights into the regulation mechanism of CaMKI.
Zha, M., Zhong, C., Ou, Y., Han, L., Wang, J., Ding, J.
Plos One