CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O00311
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O00311
CDC7_HUMAN
Homo sapiens
Cell division cycle 7-related protein kinase

PDB Structure

PDB 4F9C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human CDC7 kinase in complex with its activator DBF4.
Hughes, S., Elustondo, F., Di Fonzo, A., Leroux, F.G., Wong, A.C., Snijders, A.P., Matthews, S.J., Cherepanov, P.
Nat.Struct.Mol.Biol.