CATH Classification

Domain Context

CATH Clusters

Superfamily Helix-loop-helix DNA-binding domain
Functional Family Circadian locomoter output cycles protein kaput

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt O08785
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

O08785
CLOCK_MOUSE
Mus musculus
Circadian locomoter output cycles protein kaput

PDB Structure

PDB 4F3L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex.
Huang, N., Chelliah, Y., Shan, Y., Taylor, C.A., Yoo, S.H., Partch, C., Green, C.B., Zhang, H., Takahashi, J.S.
Science
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