CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Putative lysine-specific demethylase 6B

Enzyme Information

1.14.11.-
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q5NCY0

UniProtKB Entries (1)

Q5NCY0
KDM6B_MOUSE
Mus musculus
Lysine-specific demethylase 6B

PDB Structure

PDB 4EZ4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Kruidenier, L., Chung, C.W., Cheng, Z., Liddle, J., Che, K., Joberty, G., Bantscheff, M., Bountra, C., Bridges, A., Diallo, H., Eberhard, D., Hutchinson, S., Jones, E., Katso, R., Leveridge, M., Mander, P.K., Mosley, J., Ramirez-Molina, C., Rowland, P., Schofield, C.J., Sheppard, R.J., Smith, J.E., Swales, C., Tanner, R., Thomas, P., Tumber, A., Drewes, G., Oppermann, U., Patel, D.J., Lee, K., Wilson, D.M.
Nature
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