CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family Pirin

Enzyme Information

1.13.11.24
Quercetin 2,3-dioxygenase.
based on mapping to UniProt O00625
Quercetin + O(2) = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H(+).
-!- Quercetin is a flavonol (5,7,3',4'-tetrahydroxyflavonol).

UniProtKB Entries (1)

O00625
PIR_HUMAN
Homo sapiens
Pirin

PDB Structure

PDB 4EWD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Pirin is an iron-dependent redox regulator of NF-kappa B.
Liu, F., Rehmani, I., Esaki, S., Fu, R., Chen, L., de Serrano, V., Liu, A.
Proc.Natl.Acad.Sci.USA