CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family |
Enzyme Information
| 1.3.1.44 |
Trans-2-enoyl-CoA reductase (NAD(+)).
based on mapping to UniProt Q97LU2
Acyl-CoA + NAD(+) = trans-didehydroacyl-CoA + NADH.
-!- The enzyme from Euglena gracilis acts on crotonoyl-CoA and, more slowly, on trans-hex-2-enoyl-CoA and trans-oct-2-enoyl-CoA.
|
UniProtKB Entries (1)
| Q97LU2 |
FABV_CLOAB
Clostridium acetobutylicum ATCC 824
Trans-2-enoyl-CoA reductase [NADH]
|
PDB Structure
| PDB | 4EUE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
Biochem.J.
|
