CATH Domain 4eqyE02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1180	Udp N-acetylglucosamine O-acyltransferase; Domain 2
	1.20.1180.10	Udp N-acetylglucosamine O-acyltransferase, C-terminal domain

Domain Context

CATH Clusters

Superfamily	Udp N-acetylglucosamine O-acyltransferase, C-terminal domain
Functional Family

Enzyme Information

2.3.1.129

Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase.

based on mapping to UniProt Q2SWY6

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetyl-alpha-D- glucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)- N-acetyl-alpha-D-glucosamine.

-!- Involved with EC 2.4.1.182 and EC 2.7.1.130 in the biosynthesis of the phosphorylated glycolipid, lipid A, in the outer membrane of Escherichia coli.

UniProtKB Entries (1)

Q2SWY6

LPXA_BURTA

Burkholderia thailandensis E264

Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase

PDB Structure

PDB	4EQY
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Combining functional and structural genomics to sample the essential Burkholderia structome. Baugh, L., Gallagher, L.A., Patrapuvich, R., Clifton, M.C., Gardberg, A.S., Edwards, T.E., Armour, B., Begley, D.W., Dieterich, S.H., Dranow, D.M., Abendroth, J., Fairman, J.W., Fox, D., Staker, B.L., Phan, I., Gillespie, A., Choi, R., Nakazawa-Hewitt, S., Nguyen, M.T., Napuli, A., Barrett, L., Buchko, G.W., Stacy, R., Myler, P.J., Stewart, L.J., Manoil, C., Van Voorhis, W.C. Plos One