CATH Domain 4epiA02

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.530	Lysozyme
	1.10.530.40

Domain Context

CATH Clusters

Superfamily	1.10.530.40
Functional Family

Enzyme Information

3.2.1.17

Lysozyme.

based on mapping to UniProt P00720

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl- D-glucosamine residues in chitodextrins.

-!- Cf. EC 3.2.1.14.

UniProtKB Entries (2)

P00720	ENLYS_BPT4 Escherichia virus T4 Endolysin
Q57159	Q57159_YERPE Yersinia pestis Pesticin

PDB Structure

PDB	4EPI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural engineering of a phage lysin that targets Gram-negative pathogens. Lukacik, P., Barnard, T.J., Keller, P.W., Chaturvedi, K.S., Seddiki, N., Fairman, J.W., Noinaj, N., Kirby, T.L., Henderson, J.P., Steven, A.C., Hinnebusch, B.J., Buchanan, S.K. Proc.Natl.Acad.Sci.USA