CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1190.20
Functional Family Pyridoxal kinase

Enzyme Information

2.7.1.35
Pyridoxal kinase.
based on mapping to UniProt O00764
ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
-!- Pyridoxine, pyridoxamine and various derivatives can also act as acceptors.

UniProtKB Entries (1)

O00764
PDXK_HUMAN
Homo sapiens
Pyridoxal kinase

PDB Structure

PDB 4EN4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition.
Gandhi, A.K., Desai, J.V., Ghatge, M.S., di Salvo, M.L., Di Biase, S., Danso-Danquah, R., Musayev, F.N., Contestabile, R., Schirch, V., Safo, M.K.
Plos One
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