CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family sharpin isoform X1

Enzyme Information

UniProtKB Entries (1)

Q9H0F6
SHRPN_HUMAN
Homo sapiens
Sharpin

PDB Structure

PDB 4EMO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold.
Stieglitz, B., Haire, L.F., Dikic, I., Rittinger, K.
J.Biol.Chem.
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