CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.12350 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.12350 |
| Functional Family | Eyes absent homolog |
Enzyme Information
| 3.1.3.48 |
Protein-tyrosine-phosphatase.
based on mapping to UniProt O00167
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
|
UniProtKB Entries (2)
| P0AEX9 |
MALE_ECOLI
Escherichia coli K-12
Maltose/maltodextrin-binding periplasmic protein
|
| O00167 |
EYA2_HUMAN
Homo sapiens
Eyes absent homolog 2
|
PDB Structure
| PDB | 4EGC |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure-function analyses of the human SIX1-EYA2 complex reveal insights into metastasis and BOR syndrome.
Nat.Struct.Mol.Biol.
|