CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
Superfamily | Immunoglobulins |
Functional Family |
Enzyme Information
UniProtKB Entries (1)
P01138 |
NGF_HUMAN
Homo sapiens
Beta-nerve growth factor
|
PDB Structure
PDB | 4EDW |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs
|