CATH Classification

Domain Context

CATH Clusters

Superfamily Ricin (A subunit), domain 1
Functional Family

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P81446
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P81446
ML1_VISAL
Viscum album
Beta-galactoside-specific lectin 1

PDB Structure

PDB 4EB2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure Mistletoe Lectin I from Viscum album in complex with N-acetyl-D-glucosamine at 1.94 A resolution.
Laskov, A.A., Prokofev, I.I., Gabdoulkhakov, A.G., Betzel, C., Mikhailov, A.M.
To be Published
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