1 keywords

CATH Domain 4eafA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.1030 Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2
Homologous Superfamily 3.40.1030.10 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain
Functional Family Thymidine phosphorylase

Enzyme Information

2.4.2.4
Thymidine phosphorylase.
based on mapping to UniProt P07650
Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.
-!- In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

P07650
TYPH_ECOLI
Escherichia coli K-12
Thymidine phosphorylase

PDB Structure

PDB 4EAF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Thymidine phosphorylase from E.coli
Timofeev, V.I., Abramchik, Y.A., Esipov, R.S., Kuranova, I.P.
To be Published