CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.390 | Neutral Protease; domain 2 | |
1.10.390.10 | Neutral Protease Domain 2 |
Domain Context
CATH Clusters
Superfamily | Neutral Protease Domain 2 |
Functional Family | Aminopeptidase |
Enzyme Information
3.4.11.- |
Aminopeptidases.
based on mapping to UniProt Q6P179
|
UniProtKB Entries (1)
Q6P179 |
ERAP2_HUMAN
Homo sapiens
Endoplasmic reticulum aminopeptidase 2
|
PDB Structure
PDB | 4E36 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing.
J.Immunol.
|