CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.497 | Antithrombin; Chain I, domain 2 |
|
3.30.497.10 | Antithrombin, subunit I, domain 2 |
Domain Context
CATH Clusters
| Superfamily | Antithrombin, subunit I, domain 2 |
| Functional Family | glia-derived nexin isoform X1 |
Enzyme Information
UniProtKB Entries (1)
| P00734 |
THRB_HUMAN
Homo sapiens
Prothrombin
|
PDB Structure
| PDB | 4DY7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism.
Blood
|
