CATH Domain 4dtgK00

CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.410	Factor Xa Inhibitor
	4.10.410.10	Pancreatic trypsin inhibitor Kunitz domain

Domain Context

CATH Clusters

Superfamily	Pancreatic trypsin inhibitor Kunitz domain
Functional Family	Tissue factor pathway inhibitor

Enzyme Information

UniProtKB Entries (1)

TFPI1_HUMAN

Homo sapiens

Tissue factor pathway inhibitor

PDB Structure

PDB	4DTG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model. Hilden, I., Lauritzen, B., Sorensen, B.B., Clausen, J.T., Jespersgaard, C., Krogh, B.O., Bowler, A.N., Breinholt, J., Gruhler, A., Svensson, L.A., Petersen, H.H., Petersen, L.C., Balling, K.W., Hansen, L., Hermit, M.B., Egebjerg, T., Friederichsen, B., Ezban, M., Bjorn, S.E. Blood