CATH Classification

Domain Context

CATH Clusters

Superfamily Thymidylate synthase/dCMP hydroxymethylase domain
Functional Family Thymidylate synthase

Enzyme Information

2.1.1.45
Thymidylate synthase.
based on mapping to UniProt P67046
5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.

UniProtKB Entries (1)

P67046
TYSY_STAAM
Staphylococcus aureus subsp. aureus Mu50
Thymidylate synthase

PDB Structure

PDB 4DQ1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Thymidylate synthase from Staphylococcus aureus.
Osipiuk, J., Holowicki, J., Jedrzejczak, R., Rubin, E., Guinn, K., Ioerger, T., Baker, D., Sacchettini, J., Joachimiak, A.
To be Published
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