CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | 2-pyrone-4,6-dicarboxylate hydrolase |
Enzyme Information
| 3.1.1.57 |
2-pyrone-4,6-dicarboxylate lactonase.
based on mapping to UniProt O87170
2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = (1E)-4-oxobut-1-ene-1,2,4- tricarboxylate.
-!- The product is most likely the keto-form of 4-oxalmesaconate (shown). -!- It can be converted to the enol-form, 4-hydroxybuta-1,3-diene-1,2,4- trioate, either spontaneously or by EC 5.3.2.8.
|
UniProtKB Entries (1)
| O87170 |
LIGI_SPHSK
Sphingobium sp. SYK-6
2-pyrone-4,6-dicarboxylate hydrolase
|
PDB Structure
| PDB | 4DI8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure and Catalytic Mechanism of LigI: Insight into the Amidohydrolase Enzymes of cog3618 and Lignin Degradation.
Biochemistry
|
