CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy variable 7-81 (non-functional)

Enzyme Information

UniProtKB Entries (1)

P00746
CFAD_HUMAN
Homo sapiens
Complement factor D

PDB Structure

PDB 4D9R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibiting alternative pathway complement activation by targeting the factor d exosite.
Katschke, K.J., Wu, P., Ganesan, R., Kelley, R.F., Mathieu, M.A., Hass, P.E., Murray, J., Kirchhofer, D., Wiesmann, C., van Lookeren Campagne, M.
J.Biol.Chem.
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