CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Short-chain dehydrogenase reductase |
Enzyme Information
| 1.1.1.233 |
N-acylmannosamine 1-dehydrogenase.
based on mapping to UniProt P22441
N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + NADH.
-!- Acts on acetyl-D-mannosamine and glycolyl-D-mannosamine. -!- Highly specific.
|
UniProtKB Entries (1)
| P22441 |
DHMA_FLAS1
Flavobacterium sp. 141-8
N-acylmannosamine 1-dehydrogenase
|
PDB Structure
| PDB | 4CR7 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures and Functional Studies Clarify Substrate Selectivity and Catalytic Residues for the Unique Orphan Enzyme N-Acetyl-D-Mannosamine Dehydrogenase.
Biochem.J.
|
