CATH Classification

Domain Context

CATH Clusters

Superfamily Urease, subunit C, domain 1
Functional Family

Enzyme Information

3.5.4.42
N-isopropylammelide isopropylaminohydrolase.
based on mapping to UniProt O52063
N-isopropylammelide + H(2)O = cyanuric acid + isopropylamine.
-!- This bacterial enzyme is involved in degradation of the herbicide atrazine. -!- It can hydrolyze other N-substituted amino dihydroxy-s-triazine molecules, and prefers substrates with linear N-alkyl groups to those with branched alkyl groups. -!- Formerly EC 3.5.99.4.

UniProtKB Entries (1)

O52063
ATZC_PSESD
Pseudomonas sp. ADP
N-isopropylammelide isopropyl amidohydrolase

PDB Structure

PDB 4CQC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-Ray Structure and Mutagenesis Studies of the N-Isopropylammelide Isopropylaminohydrolase, Atzc
Balotra, S., Warden, A.C., Newman, J., Briggs, L.J., Scott, C., Peat, T.S.
Plos One