CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.141 | Nucleoside diphosphate kinase-like domain |
Domain Context
CATH Clusters
| Superfamily | Nucleoside diphosphate kinase-like domain |
| Functional Family | Nucleoside diphosphate kinase |
Enzyme Information
| 2.7.4.6 |
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22887
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
|
UniProtKB Entries (1)
| P22887 |
NDKC_DICDI
Dictyostelium discoideum
Nucleoside diphosphate kinase, cytosolic
|
PDB Structure
| PDB | 4CP5 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity.
Antiviral Res.
|
