CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Pteridine reductase

Enzyme Information

UniProtKB Entries (1)

O76290
O76290_TRYBB
Trypanosoma brucei brucei
Pteridine reductase

PDB Structure

PDB 4CLR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1.
Khalaf, A.I., Huggan, J.K., Suckling, C.J., Gibson, C.L., Stewart, K., Giordani, F., Barrett, M.P., Wong, P.E., Barrack, K.L., Hunter, W.N.
J.Med.Chem.