CATH Domain 4cl8A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family	Pteridine reductase

Enzyme Information

UniProtKB Entries (1)

O76290_TRYBB

Trypanosoma brucei brucei

Pteridine reductase

PDB Structure

PDB	4CL8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1. Khalaf, A.I., Huggan, J.K., Suckling, C.J., Gibson, C.L., Stewart, K., Giordani, F., Barrett, M.P., Wong, P.E., Barrack, K.L., Hunter, W.N. J.Med.Chem.