CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.60 | Sandwich | |
2.60.40 | Immunoglobulin-like | |
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
Superfamily | Immunoglobulins |
Functional Family | Vascular endothelial growth factor receptor 1 |
Enzyme Information
2.7.10.1 |
Receptor protein-tyrosine kinase.
based on mapping to UniProt P17948
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- The receptor protein-tyrosine kinases, which can be defined as having a transmembrane domain, are a large and diverse multigene family found only in metazoans. -!- In the human genome, 58 receptor-type protein-tyrosine kinases have been identified and these are distributed into 20 subfamilies. -!- Formerly EC 2.7.1.112.
|
UniProtKB Entries (1)
P17948 |
VGFR1_HUMAN
Homo sapiens
Vascular endothelial growth factor receptor 1
|
PDB Structure
PDB | 4CL7 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Biophysical Studies of the Induced Dimerization of Human Vegf R Receptor 1 Binding Domain by Divalent Metals Competing with Vegf-A
Plos One
|