CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.58.1480
Functional Family Cereblon, isoform CRA_c

Enzyme Information

UniProtKB Entries (2)

P0CF65
CRBN_CHICK
Gallus gallus
Protein cereblon
Q16531
DDB1_HUMAN
Homo sapiens
DNA damage-binding protein 1

PDB Structure

PDB 4CI3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Fischer, E.S., Bohm, K., Lydeard, J.R., Yang, H., Stadler, M.B., Cavadini, S., Nagel, J., Serluca, F., Acker, V., Lingaraju, G.M., Tichkule, R.B., Schebesta, M., Forrester, W.C., Schirle, M., Hassiepen, U., Ottl, J., Hild, M., Beckwith, R.E.J., Harper, J.W., Jenkins, J.L., Thoma, N.H.
Nature
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