CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.170 | Beta Complex | |
2.170.150 | Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A | |
2.170.150.20 | Peptide methionine sulfoxide reductase. |
Domain Context
CATH Clusters
Superfamily | Peptide methionine sulfoxide reductase. |
Functional Family | Cereblon, isoform CRA_c |
Enzyme Information
UniProtKB Entries (2)
P0CF65 |
CRBN_CHICK
Gallus gallus
Protein cereblon
|
Q16531 |
DDB1_HUMAN
Homo sapiens
DNA damage-binding protein 1
|
PDB Structure
PDB | 4CI3 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature
|