CATH Classification
Level | CATH Code | Description |
---|---|---|
![]() |
2 | Mainly Beta |
![]() |
2.40 | Beta Barrel |
![]() |
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
![]() |
2.40.50.170 | Cysteine proteinases. Chain C |
Domain Context
CATH Clusters
Superfamily | Cysteine proteinases. Chain C |
Functional Family |
Enzyme Information
3.4.14.1 |
Dipeptidyl-peptidase I.
based on mapping to UniProt P53634
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.
-!- Also polymerizes dipeptide amides, arylamides and esters at neutral pH. -!- Cl(-)-dependent lysosomal cysteine-type peptidase. -!- Belongs to peptidase family C1. -!- Formerly EC 3.4.4.9.
|
UniProtKB Entries (1)
P53634 |
CATC_HUMAN
Homo sapiens
Dipeptidyl peptidase 1
|
PDB Structure
PDB | 4CDC |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate.
J.Med.Chem.
|