CATH Domain 4cclA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.366	Malonyl-Coenzyme A Acyl Carrier Protein; domain 2
	3.40.366.30	50S ribosomal protein L16 arginine hydroxylase; Chain A, Domain 2

Domain Context

CATH Clusters

Superfamily	50S ribosomal protein L16 arginine hydroxylase; Chain A, Domain 2
Functional Family

Enzyme Information

1.14.11.47

[50S ribosomal protein L16]-arginine 3-hydroxylase.

based on mapping to UniProt P27431

[50S ribosomal protein L16]-L-Arg(81) + 2-oxoglutarate + O(2) = [50S ribosomal protein L16]-(3R)-3-hydroxy-L-Arg(81) + succinate + CO(2).

-!- The enzyme, characterized from the bacterium Escherichia coli, hydroxylates an arginine residue on the 50S ribosomal protein L16, and is involved in regulation of bacterial ribosome assembly.

UniProtKB Entries (1)

P27431

ROXA_ECOLI

Escherichia coli K-12

50S ribosomal protein L16 3-hydroxylase

PDB Structure

PDB	4CCL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Chowdhury, R., Sekirnik, R., Brissett, N.C., Krojer, T., Ho, C.H., Ng, S.S., Clifton, I.J., Ge, W., Kershaw, N.J., Fox, G.C., Muniz, J.R.C., Vollmar, M., Phillips, C., Pilka, E.S., Kavanagh, K.L., von Delft, F., Oppermann, U., McDonough, M.A., Doherty, A.J., Schofield, C.J. Nature