CATH Classification

Domain Context

CATH Clusters

Superfamily Cupin
Functional Family Cupin superfamily protein family

Enzyme Information

1.14.11.47
[50S ribosomal protein L16]-arginine 3-hydroxylase.
based on mapping to UniProt P27431
[50S ribosomal protein L16]-L-Arg(81) + 2-oxoglutarate + O(2) = [50S ribosomal protein L16]-(3R)-3-hydroxy-L-Arg(81) + succinate + CO(2).
-!- The enzyme, characterized from the bacterium Escherichia coli, hydroxylates an arginine residue on the 50S ribosomal protein L16, and is involved in regulation of bacterial ribosome assembly.

UniProtKB Entries (1)

P27431
ROXA_ECOLI
Escherichia coli K-12
50S ribosomal protein L16 3-hydroxylase

PDB Structure

PDB 4CCL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Chowdhury, R., Sekirnik, R., Brissett, N.C., Krojer, T., Ho, C.H., Ng, S.S., Clifton, I.J., Ge, W., Kershaw, N.J., Fox, G.C., Muniz, J.R.C., Vollmar, M., Phillips, C., Pilka, E.S., Kavanagh, K.L., von Delft, F., Oppermann, U., McDonough, M.A., Doherty, A.J., Schofield, C.J.
Nature
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