CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family galactocerebrosidase precursor

Enzyme Information

3.2.1.46
Galactosylceramidase.
based on mapping to UniProt P54818
D-galactosyl-N-acylsphingosine + H(2)O = D-galactose + N-acylsphingosine.
-!- Cf. EC 3.2.1.62.

UniProtKB Entries (1)

P54818
GALC_MOUSE
Mus musculus
Galactocerebrosidase

PDB Structure

PDB 4CCE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Hill, C.H., Graham, S.C., Read, R.J., Deane, J.E.
Proc.Natl.Acad.Sci.USA